Police are at the scene of serious collision at Aveton Gifford near Kingsbridge.
Officers were called at just before 3.30pm on Friday 13 September following the collision involving two cars and a motorcycle on the A379 by Ashford.
Ambulance and the air ambulance are on scene.
The male motorcyclist has sustained serious injuries. He is being taken to Derriford Hospital.
The A379 is currently blocked and closed by police.